Abstract
Self-injurious behavior (SIB) in patients with borderline personality disorder (BPD) has traditionally been understood in psychodynamic (Kafka, 1969: Menninger, 1935; Pao, 1969; Simpson, 1975) and behavioral (Linehan, 1989) terms. More recently, investigators have suggested that specific biological mechanisms are significantly related to SIB in patients with BPD. We review the neurochemical, electrophysiological, and psychopharmacological data that directly and indirectly address this issue.
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