Self-assembled nanotube field-effect transistors for label-free protein biosensors

Abstract

A self-assembly method is developed to fabricate single-wall carbon nanotube field-effect transistors (SWNT-FETs). The electrode surface and the area between electrodes are modified with nonpolar groups (−CH3) and polar groups (−NH3+). SWNTs are selectively placed in the area between the electrodes. We achieve stability and specificity in label-free protein detection using the biotin-streptavidin pair as research model. Our process holds promise for high integration of SWNT-FET biosensors, with no need for high-temperature processing.