Abstract
The interrelationships among sensitivity, tolerance and the self-administration of ethanol were studied in a non-inbred strain of mice. Blood ethanol concentration at the time of righting-loss following a hypnotic dose of ethanol (3.5 g/kg) was measured before and after 8 weeks exposure to a choice of water and ethanol water drinking solutions. The inter-test difference between blood ethanol concentration at loss of righting indicated that self-administration resulted in chronic tolerance. A correlational analysis indicated chronic tolerance, but not sensitivity, was positively correlated with ethanol intake and preference.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
