Abstract
Monophasic hypothalamic s elf-stimulation via bipolar electrodes was compared in four rats and three rock squirrels. During two blocks, the first of four and the second of six test days, response rates for squirrels declined over days unlike those for rats. No evidence was found that differences in electrode loci, tissue injury, or impedance changes contributed to the species difference. When pulse polarity was systematically varied, rates for each current direction differed markedly irrespective of species or interval between successive polarity alternations.
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