Abstract
BackgroundWe investigated the relation of self-reported snoring with carotid intima-media thickness (IMT) and plaque in community-dwelling middle-aged and older adults.MethodsIn total, 7330 community-dwelling subjects in the Korean Multi-Rural Communities Cohort Study were included in the analysis. Common carotid artery IMT (CCA-IMT) and plaque were evaluated by high-resolution B-mode ultrasonography. Snoring status was evaluated using a structured interview.ResultsSnorers had a significantly greater average CCA-IMT than non-snorers (0.726 vs 0.713 mm; P < 0.001), after adjusting for age and gender. The odds ratios (OR) for high CCA-IMT (fifth quintile) were significantly higher for snorers than for non-snorers in multivariate-adjusted analysis (OR 1.25, 95% confidence interval [CI] 1.10–1.42). However, there was no significant relationship between snoring and carotid plaques.ConclusionsOur data suggest that self-reported snoring is significantly associated with increased IMT, but not with the presence of plaques. These findings suggest that early screening and intervention for snoring in the general population are needed to prevent adverse cardiovascular events.
Highlights
Snoring is a sound emitted from the upper airway of the throat during sleep and is an indicator of increased resistance through the airway.[1]
Since previous epidemiologic studies have suggested that snoring is significantly associated with metabolic syndrome,[14,15] metabolic components have been considered as the link between snoring and cardiovascular disease (CVD)
Whether or not self-reported snoring is significantly associated with carotid atherosclerosis in the general population remains undetermined
Summary
Snoring is a sound emitted from the upper airway of the throat during sleep and is an indicator of increased resistance through the airway.[1]. A non-metabolic pathway that mediates the relationship between snoring and CVD, such as carotid atherosclerosis, has been proposed.[16,17] Increased carotid intima-media thickness (IMT) and atherosclerotic plaques are surrogate markers of subclinical atherosclerosis and strong predictors of CVD, such as stroke and myocardial infarction.[18,19] Few epidemiologic studies have examined the association between snoring and carotid atherosclerosis; those that did reported inconsistent associations.[20,21] To date, whether or not self-reported snoring is significantly associated with carotid atherosclerosis in the general population remains undetermined. We investigated the relation of self-reported snoring with carotid intima-media thickness (IMT) and plaque in community-dwelling middle-aged and older adults. Conclusions: Our data suggest that self-reported snoring is significantly associated with increased IMT, but not with the presence of plaques. These findings suggest that early screening and intervention for snoring in the general population are needed to prevent adverse cardiovascular events
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