Self-assembly of a nucleotide-calixarene hybrid in a triangular supramolecule

Abstract

The self-assembly of a thymine nucleotide-calixarene hybrid ( 1) in CDCl 3 as a solvent was investigated. FT-IR, ESI-MS, 1H and DOSY-NMR spectra evidenced that compound 1 (ammonium or sodium salt) self-assembles in a triangular trimeric supramolecule by thymine–thymine hydrogen bonding. The saline form is crucial for the arrangement in the cyclic trimer as the protonation of the nucleotide phosphate groups leads the assembly toward a dimeric species.