Abstract
A new series of selenolo[2,3-b]quinoline, pyrimido[4′,5′:4,5]selenolo[2,3-b]quinoline, pyrimido[4′,5′:4,5]selenolo[2,3-b]-[1,2,4′triazolo[1,5-c]quinoline, and pyrimido[4′,5′:4,5]selenolo[2,3-b][1,2,4]triazolo[4,3-c]quinoline derivatives were prepared starting from diquinolinyl diselenide or 3-cyano-4-methylquinoline-2(1H)selenone with chloro acetonitrile or chloro acetamide. Elemental analysis, IR, 1H NMR, 13C NMR, and mass spectral data confirmed the structure of the newly synthesized compounds. In addition, the most active compounds were tested for their acute toxicity. Moreover, some of the tested compounds were screened for their antibacterial and antifungal activities. The minimum inhibitory concentration (MIC) of the most active compounds was 100 mg mL−1. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
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