Abstract
The effects of intravenous isoprenaline and salbutamol were compared in fifteen asthmatic patients. The two drugs were found on average to be equipotent as bronchodilators. Salbutamol was seven times less potent than isoprenaline in raising the heart rate. Both drugs increased alveolar ventilation to the same extent, and mean arterial oxygen tension rose by a few mm Hg with both drugs. The physiological significance of these changes and of asthma becoming resistant to isoprenaline are discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have