Abstract
Three divergent Direct Imine Acylation (DIA) procedures are reported that allow the selective generation of δ-lactams, β-lactams and tetrahydropyrimidinones (via a novel three-component coupling) from imine and carboxylic acid precursors. All operate via initial N-acyliminium ion formation and diverge depending on the reaction conditions and nature of the substrates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have