Selective Sorption of Endotoxin in Combined Therapy of Post-Traumatic Abdominal Sepsis

Abstract

The investigations of the dynamics of lipopolysaccharide and presepsin in patients with closed abdominal trauma in the early post-traumatic period and after the development of abdominal sepsis. It revealed a biphasic rise of sepsis markers on stage fill hypovolemia and sepsis during subsequent development. High-performance determined early consistent application of selective sorption of lipopolysaccharide using «LPS adsorber» (Alteco, Sweden) and prolonged veno-venous hemofiltration in relation to the relief of endotoxemia and prevent the progression of multiple organ failure at post-traumatic abdominal sepsis.