Abstract
A near-infrared fluorescent (NIR) probe NR-Zn, which consists of a dicyanoisophorone derivative and an Zn(II) ion recongnitive dipicolylamine moiety, was synthesized and applied to detect Zn(II) ions concentration change in living cell. This NR-Zn probe exhibits a strong turn-on fluorescence response toward Zn(II) ions when excited at 545 nm and has other advantages, such as rapid response (<20 s), large Stokes shift (131 nm), low cytotoxicity and good photostability. Moreover, it has been succesfully applied to monitor Zn(II) ions in Hela cells.
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