Abstract

On the loose end. We report a quinoline derivative (QD1; highlighted in blue in the scheme) that is selective for RNA helices that contain 3′-dangling ends. The selectivity depends on the length and sequence of the dangling 3′ end and the terminal base pair of the helix. These results identify QD1 as a promising scaffold for designing structure specific RNA-binding ligands. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2268/2007/z700261_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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