Abstract
Oral Newcastle disease vaccine, strain V4, was administered to an open-range multi-age chicken flock. Adult birds in this flock had low levels of haemagglutination inhibition antibody as a result of vaccination of the flock with strain V4 more than 3 years previously and apparent persistence of the vaccine virus. Eight clutches of chicks were hatched over a period of 3 months. Vaccine, given at fortnightly intervals, was restricted to young chicks by creep feeding. Chicks in all the clutches produced antibody in response to vaccination, and levels of antibody in the adult flock increased as the first clutches were responding to vaccination. When oral vaccine is used in the field, restriction of vaccination to chicks could conserve without reducing the efficacy of vaccination.
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