Selective One‐Pot Access to Symmetrical or Unsymmetrical Diaryl Ethers by Copper‐Catalyzed Double Arylation of a Simple Oxygen Source

Abstract

Great CO-mbination: A novel method is reported for the controlled one-pot synthesis of various symmetrical or unsymmetrical diaryl ethers by double arylation of a simple inorganic oxygen source (see scheme). This versatile and highly selective process is based on the use of a cheap and low toxicity copper catalytic system.