Selective N‐Deacetylation and Functionalization of Aminosugars

Abstract

AbstractN‐Acetyl groups are abundant functional groups found in a variety of biomolecules including aminosugars. N‐Acetyl groups are chemically stable and harsh conditions are often needed to remove them. Herein, we report a mild and efficient protocol to remove N‐acetyl groups in the presence of esters and carbamates and functionalize the resulting amine in a one‐pot manner.