Abstract
Abstract: This study assessed the pattern of memory performance both in working memory components and episodic long-term memory in a sample of 30 schizophrenic patients, showing intact intellectual and attentional functions. The patients were compared with 30 alcoholics and 30 normal control subjects, matched for age, sex and estimated premorbid IQ. Intellectual functions, assessed using a short form of WAIS, showed no deficits in estimated Full-Scale IQ between the three groups. Attention, working memory, verbal and visual long-term memory were assessed by the subtests of WMS-R. Schizophrenic patients only showed poor overall performance in verbal and visual long-term memory, whereas alcoholics showed a broader pattern of cognitive dysfunction including attentional, working memory and verbal long-term memory components. Taken together the neuropsychological pattern of intact working memory components and impaired long-term memory in schizophrenia is similar to the classic amnesic syndrome and suggest a selective medial temporal-hippocampal dysfunction.
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