Selective laser trabeculoplasty: Results on intraocular pressure and number of topical antiglaucoma medications

Abstract

PurposeTo evaluate results at one year of selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) and assess if differences are related to number of topical treatments in ocular hypertension (OHT) and open angle glaucoma (OAG) patients.MethodsWe performed a retrospective chart review of 106 eyes treated by SLT. Indications for SLT treatment were insufficient IOP control, allergy, discomfort or non‐compliance to antiglaucoma treatment. Only patients with at least 1 year of follow‐up after SLT were included. IOP was measured before and at 1, 6 and 12 months after SLT. All IOP measurements were performed with Goldmann applanation tonometry.Results106 eyes of 68 patients untreated (n = 13), or treated with one (n = 25), two (n = 39) or three (n = 28) topical antiglaucoma medications were included. Mean preoperative IOP was 19.4 ± 3.6 mmHg (respectively 21.1 ± 2.7, 19.8 ± 3.1, 19.1 ± 4.2 and 18.9 ± 3.4 mmHg corresponding to the group without, one, two or three treatments) and 15.7 ± 3.1 mmHg at 12 months (respectively 16.2 ± 3.5, 15.6 ± 2.6, 15.6 ± 3.4 and 15.5 ± 2.8 mmHg for each groups) which corresponds to an average decrease of 18.3% (respectively 23.7%, 19.7%, 17.2% and 16.1% for each groups). At 1 year, 62.2% (n = 66) were responders (≥3 mmHg reduction from baseline IOP = 15.5% of IOP baseline): 92.3% without treatment (n = 12), 68% with one (n = 17), 59% with two (n = 23) and 50% with three treatments (n = 14). The average IOP of responders decreased from 20.7 ± 3.4 to 15.2 ± 2.9 mmHg (26.6%), respectively from 20.8 ± 2.6 to 15.8 ± 3.2 (25%) without treatment, from 20.6 ± 3.2 to 14.9 ± 3.7 (27.3%) with one, from 20.8 ± 4.1 to 15.5 ± 3.3 (25.1%) with two and from 20.7 ± 3.2 to 14.4 ± 2.4 mmHg (29.7%) with three treatments.ConclusionsLowering of IOP and number of responders after SLT appears to be more important un OHT and OAG patients with less topical antiglaucoma treatment.