Selective Internal Radiotherapy (SIRT) of Primary Hepatic Carcinoma and Liver Metastases

Abstract

SIRT (selective internal radiation therapy) is a widely used form of intra-arterial treatment for patients with advanced liver primary and secondary tumors of the liver. The relatively selective arterial perfusion via the hepatic artery of growing liver tumors makes intra-arterial treatment an near ideal concept for these patients. Nevertheless the procedure needs technical and dosimetry skills which are summarized in this chapter. Furthermore, the clinical data in context to intravenous therapies need to be acknowledged mainly in discussion with multidisciplinary tumor boards. Therefore this chapter also summarizes important studies in the field. Finally, measurement outcome remains a challenge and are also discussed in the last paragraph.