Abstract

Light-activated receptor currents were measured in Limulus ventral nerve photoreceptors by a two electrode voltage clamp. Short flashes stimulate three different current components (C1, C2, C3). Currents were measured before and after injection of neomycin, heparin and BAPTA. These substances inhibit the inositol phosphate pathway at different stages. Each substance selectively blocked the C2 component. After the block of C2 the other two components could be further stimulated, but their amplitudes were usually reduced. High concentrations of BAPTA, however, increased the amplitude (two-fold) and decay time constant (eight-fold) of C1, suggesting that calcium is necessary for the deactivation of the C1 current.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.