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https://doi.org/10.1007/bf00207189
Copy DOIJournal: Journal of Comparative Physiology A | Publication Date: Oct 1, 1995 |
Citations: 39 |
Light-activated receptor currents were measured in Limulus ventral nerve photoreceptors by a two electrode voltage clamp. Short flashes stimulate three different current components (C1, C2, C3). Currents were measured before and after injection of neomycin, heparin and BAPTA. These substances inhibit the inositol phosphate pathway at different stages. Each substance selectively blocked the C2 component. After the block of C2 the other two components could be further stimulated, but their amplitudes were usually reduced. High concentrations of BAPTA, however, increased the amplitude (two-fold) and decay time constant (eight-fold) of C1, suggesting that calcium is necessary for the deactivation of the C1 current.
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