Selective Immunoglobulin M Deficiency and Terminal Ileitis due to Yersinia Enterocolitica Infection: A Clinically Interesting Coexistence

Abstract

Selective IgM deficiency is a rare type of dysgammaglobulinemia characterized by low levels of serum IgM and repeated multisystemic infections. Yersiniosis is a food-borne disease that has become more prevalent recently due to human transmission via the fecal-oral route and its occurrence in farm animals. No clinically obvious development of Yersiniosis in patients with selective IgM deficiency has been described so far. The present report describes a patient with selective IgM deficiency who presented with repeated microbial infections and terminal ileitis due to Yersinia infestation.