Selective fiber optic TFBG-assisted biosensors featuring functional coatings

Abstract

The paper reports on the results of the development of tilted fiber Bragg grating-assisted selective biosensors. The main sensing principle is based on the dependence of an optical evanescent field parameters on the composition of the medium under study. Sensors feature functional coatings of antibodies against protein molecules common in blood composition – fibrinogen and D-dimer. The work explores and clearly demonstrates the selective sensitivity of sensors to specific proteins by the example of simultaneous measurements using a pair of sensors functionalized with different antibodies.