Abstract

AbstractThe addition of sodium dodecylsulfate (SDS) to a glycerol solution containing equal concentrations of a series of quaternary amines has been found to have a significant effect on the relative fast atom bombardment (FAB) response factors for each analyte. The relative FAB signals of quaternary amines with different alkly chain length were found to be either enhanced or degraded under different SDS concentrations. The effect observed can be correlated with the difference in the rate of ion‐pair precipitate formation between negatively charged dodecylsulfate and positively charged quaternary amine. It is also demonstrated that, in much the same way, SDS can be used to enhance the response of the less surface‐active component in an industrial dye by FAB analysis.

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