Abstract
Peptides are natural messenger molecules of human body and hence ideal lead compounds for the initiation of drug discovery research. They are the important organic compounds with potent biological activities. Peptides functions as hormones, enzymes enzyme inhibitors, or substrates or growth inhibitors or promoters, neurotransmitters and immunomodulators. Investigation of new and more potent analogs of molecules with already established activities from a key part of research in pharmaceutical field. It’s brings many modifications by manipulates the parent molecules structures serves to increase the activity of the compound, also eliminate adverse effect or toxicity associated with the parent drug. Cancer is the leading cause of deaths in world, We evaluated four natural cyclopeptides Diandrine A, Diandrine C, Fanlizhicyclopeptide A, Fanlizhicyclopeptide B, for cytotoxicity against HCT116 (Human Colorectal Carcinoma) and B16F10 (musculus skin melanoma) cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: International Journal of Pharmaceutical Sciences and Drug Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.