Abstract
Calcium oxalate (CaOx) is the main compound of human kidney stones, specifically calcium oxalate monohydrate crystals (COM). Normal human urine contains small crystals of calcium oxalate dihydrate (COD), which have reduced capacity to form stable aggregates and strong adhesion contacts to renal epithelial cell thus protecting kidney stone formation. Here, we report the preparation of a new monomethylitaconate grafted polymethylsiloxaner, which was able to promote and stabilize COD crystals. Although the mechanisms involved in control of CaOx polymorphism still remain unclear, we believe that research using synthetic polymers would provide interesting chemical clues to develop calculi preventing-compounds.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
