Abstract

Hydrogenation of nitro groups to produce anilines is a well-established transformation in organic chemistry and the pharmaceutical industry [1]. However, high pressure hydrogenations can be hazardous at multi-kilo scales and functional group compatibly is often problematic for pharmaceutical intermediates requiring a specialized catalyst [2]. In a continued effort to promote electrochemistry in pharma as a greener and safer alternative, an improved method of electrochemically producing anilines has been achieved. In this presentation, the development of a robust and efficient undivided Aryl-nitro reduction will be discussed.

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