Selective and Sensitive Electrochemical Sensor for L‐Methionine at Physiological pH Using Functionalized Triazole Polymer Film Modified Electrode

Abstract

AbstractThis communication describes the determination of an essential amino acid, L‐methionine (L‐Met) in the presence of important interferents, ascorbic acid (AA) and uric acid (UA) at physiological pH using a glassy carbon electrode modified with an electropolymerized film of 3‐amino‐5‐mercapto‐1,2,4‐triazole (p‐AMTa). The bare glassy carbon electrode fails to show a voltammetric signal for L‐Met in the presence of AA and UA at pH 7.2. However, the p‐AMTa electrode separates the voltammetric signals of AA, UA and L‐Met with pronounced oxidation currents. The amperometric current of L‐Met was increased linearly from 1.0×10−7 to 1×10−4 M and the detection limit was found to be 4.12×10−10 M (S/N=3).