Abstract
The effects of short chain alcohols (1 through 4 carbons) on hepatic cyclase were examined. Alcohol produced a reversible activation of the glucagon responsive cyclase but did not activate the epinephrine responsive component. The activation was accompanied by changes in the kinetic properties of the glucagon responsive cyclase and could not be explained in terms of enhanced Mg†† binding. These changes could reflect modifications of the solvent environment or binding of alcohol to a single site on the enzyme. The selective nature of this activation further emphasizes the differences in the properties of the 2 hepatic cyclase systems. (Endocrinology 87: 1075, 1970)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
