Abstract
The influence of the model used to describe the basic competitive interactions between a stationary phase and migrating solutes was investigated to simulate reversed-phase displacement chromatography. Experimental separations of catechol—resorcinol mixtures using phenol as the displacer were compared with numerical simulations. The competitive Langmuir model, the LeVan—Vermeulen model and the quadratic model were chosen to describe the competitive adsorption equilibria. These models were related either to their non-competitive parameters or to their competitive parameters. A novel simplified experimental procedure is proposed to obtain competitive parameters for a binary mixture. The chromatographic process is described by the equilibrium-dispersive model and the calculations were performed by using a finite difference method. The results demonstrated that competitive isotherm equations with numerically fitted parameters do not lead to a good description of a displacement separation process. On the other hand, the LeVan—Vermeulen isotherm, with non-competitive Langmuir parameters, was found to be a relevant choice to the experimental conditions involved.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
