Selection for Extremes in Serum FSH Concentrations Results in Reduced Testis Size and Fertility in Meishan and White Composite Boars

Abstract

The Meishan breed of swine was imported from China for its high ovulation rate and as a model to increase fecundity in the swine industry. Concentrations of follicle stimulating hormone (FSH) are increased in Meishan boars (5 to 10 x) as compared to European breeds utilized for meat production in the United States. In human reproduction, elevated FSH concentrations in men are associated with impaired gonadal function and infertility. In the current studies, concentrations of serum FSH were related negatively to testis size and weights in Meishan boars and White composite boars of European origin. Selection for high FSH concentrations in boars was correlated with reduced testis weight and fertility, all common characteristics of hypergonadotropism associated infertility in men. Meishan boars that have extremes in FSH concentrations and testis weights may be a useful model for the study of hypergonadotropic hypogonadal function in men.†