Abstract

The study of postural sway has important implications for sports, rehabilitation and aging. Postural sway can be quantitated by analyzing the excursions of the center of pressure (COP) obtained using a force platform. As part of a study investigating the effects of triazolam on postural sway we compared two measures of sway, radial area (RD) and elliptical area (EL), in order to determine which demonstrated greater clinical utility. In a double blind randomized study, six healthy men received triazolam and placebo orally, followed by measurement of postural sway at multiple time points. EL contained a larger percentage of the COP points than RD. Tte mcan ratio of the two areas and the mean eccentricity of EL were highly variable suggesting that EL is not simply a scaled up version of the RD. Finally, EL showed greater sensitivity in distinguishing drug effect from placebo. In conclusion, EL provides a better representation of the sway data and may demonstrate greater clinical utility.

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