Selección de lo mejor del año 2018 en denervación simpática renal en el tratamiento de la hipertensión arterial

Abstract

Hypertension is a highly prevalent cardiovascular risk factor that is difficult to control despite the evolution of pharmacological treatment. Percutaneous renal denervation is a procedure that aims to modulate the sympathetic nervous system directly involved in the pathophysiology of hypertension. Despite promising initial results, the SYMPLICITY HTN-3 study failed to demonstrate the efficacy of renal denervation in the treatment of hypertension resistant to drug treatment. Subsequent analysis of the study results revealed potential confounding factors that could explain, at least in part, the unexpected results of the study. Recent studies with a limited number of patients have demonstrated the efficacy of renal denervation in the treatment of moderate hypertension and in the absence of pharmacological treatment. Although the role of renal denervation in the treatment of hypertension is still to be determined, the results of recent studies open a field of applications that should be explored in the coming years.