Abstract
Objective To study factors impacting on the outcome of surgery in intractable temporal lobe epilepsy with hippocampal sclerosis in children.Methods Between June 2010 and June 2012,clinical data of 25 pediatric patients with temporal lobe epilepsy haboring hippocampal sclerosis were collected in neurosurgical department of Beijing Tiantan Hospital.Seizure outcome was evaluated with Engel class.The correlation among age at seizure onset,sex,seizure frequency,duration of seizure,age at operation,MRI findings,pathological features and seizure outcome were assessed.Results Seven patients were confirmed as FCD Ⅲ a by neuropathology and others were hippocampal sclerosis only.Duration of seizure is a risk factor to affect the outcome of operation (P ＜ 0.05),but other factors have minor impact on the outcome of operation(P ＞ 0.05).Conclusion Early operation of temporal lobe epilepsy with hippocampal sclerosis in children predicts a better outcome.The correlation between the pathological lesions and surgical effects should be paid more attention for further study. Key words: Epilepsy ; Child ; Hippocampal sclerosis ; Focal cortical dysplasia Ⅲ a
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
