Abstract
Vagus nerve stimulation (VNS) is generally considered as a palliative treatment for patients with drug-resistant partial-onset epilepsy. We report a case in which a patient with drug-resistant epilepsia partialis continua (EPC), became seizure-free for 15 months with VNS combined with antiepileptic medication regimens. To our knowledge, similar cases have not been reported previously.
Highlights
Vagus nerve stimulation (VNS) is an effective adjunctive therapy for patients with drug-resistant partial-onset epilepsy [1]
We report that a patient became seizure-free in epilepsia partialis continua (EPC) with VNS therapy combined with antiepileptic drug (AED) regimens
The patient had two prominent twitches of the mouth per week. His stimulation current output was changed to 0.50 mA, and his seizures became countless as they were pre-operation
Summary
Vagus nerve stimulation (VNS) is an effective adjunctive therapy for patients with drug-resistant partial-onset epilepsy [1]. It decreases seizure frequency by approximately 50% in 30–40% of implanted patients [2]. The efficacy of VNS has been demonstrated in treating various types of generalized epilepsies, including genetic generalized epilepsy (GGE) and Lennox–Gastaut syndrome [3]. We report that a patient became seizure-free in epilepsia partialis continua (EPC) with VNS therapy combined with antiepileptic drug (AED) regimens
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