Seigo Shima

Abstract

Angewandte Chemie International EditionVolume 58, Issue 24 p. 7910-7910 Author ProfileFree Access Seigo Shima First published: 17 January 2019 https://doi.org/10.1002/anie.201900274AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “I am waiting for the day when someone will discover a method to predict earthquakes. If I could be described as an animal it would be a mouse …” Find out more about Seigo Shima in his Author Profile. Seigo Shima The author presented on this page has published more than 10 articles in Angewandte Chemie in the last 10 years, most recently: “The bacterial [Fe]-hydrogenase paralog HmdII uses tetrahydrofolate derivatives as substrates”: T. Watanabe, T. Wagner, G. Huang, J. Kahnt, K. Ataka, U. Ermler, S. Shima, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201813465; Angew. Chem. 2019, DOI: 10.1002/ange.201813465. The work of S. Shima has been featured as a frontispiece communication in Angewandte Chemie: “Crystal Structures of [Fe]-Hydrogenase in Complex with Inhibitory Isocyanides: Implications for the H2-Activation Site”: H. Tamura, M. Salomone-Stagni, T. Fujishiro, E. Warkentin, W. Meyer-Klaucke, U. Ermler, S. Shima, Angew. Chem. Int. Ed. 2013, 52, 9656; Angew. Chem. 2013, 125, 9838. Date of birth: November 5, 1960 Position: Research Group Leader at the Max Planck Institute for Terrestrial Microbiology, Guest Professor at The Institute of Low Temperature Science at Hokkaido University E-mail: shima@mpi-marburg.mpg.de Homepage: https://www.mpi-marburg.mpg.de/shima ORCID: org/0000-0003-1872-8705 Education: 1985 Master, Osaka Prefectural University 1991 Ph.D., Prof. Tohru Kodama, University of Tokyo 1993–1995 Alexander von Humboldt Research Fellow, Prof. Rudolf K. Thauer, Philipps Universität Marburg Awards: 2013 JSPS Alumni Club Award, 2013 The conversion of light energy prize from a PRESTO program of Japan Science and Technology Agency Research: Catalytic mechanisms of metalloenzymes, biosynthesis of metallocofactors Hobbies: Do-it-yourself, walking, listening to music My motto is “relax and enjoy”. When I was eighteen I wanted to be a microbiologist. If I could be described as an animal it would be a mouse. I am waiting for the day when someone will discover a method to predict earthquakes. The biggest challenge facing scientists is climate change. Science is fun because we can directly learn from nature. My favorite drink is Port Wine. My first experiment was bacterial-colony counting. My favorite time of day is walking in the forest to the institute. My favorite way to spend a holiday is to visit restaurants in foreign towns. My favorite name of molecule is the FeGP cofactor. If I could be a piece of lab equipment, I would be a balance. My favorite painter is Günter Blau. My favorite composer is Johann Sebastian Bach. My 5 top papers: 1“A conspicuous nickel protein in microbial mats that oxidize methane anaerobically”: M. Krüger, A. Meyerdierks, F. O. Glöckner, R. Amann, F. Widdel, M. Kube, R. Reinhardt, J. Kahnt, R. Böcher, R. K. Thauer, S. Shima, Nature 2003, 426, 878. We isolated and characterized nickel enzymes that catalyze the anaerobic oxidation of methane. 2“The Crystal Structure of [Fe]-Hydrogenase Reveals the Geometry of the Active Site ”: S. Shima, O. Pilak, S. Vogt, M. Schick, M. S. Stagni, W. Meyer-Klaucke, E. Warkentin, R. K. Thauer, U. Ermler, Science 2008, 321, 572. We proposed a model of the iron center of [Fe]-hydrogenase. 3“Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically”: S. Shima, M. Krueger, T. Weinert, U. Demmer, J. Kahnt, R. K. Thauer, U. Ermler, Nature 2012, 481, 98. We crystallized a methane-oxidizing enzyme from a protein mixture prepared from the natural microbial mat. 4“The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters”: T. Wagner, U. Ermler, S. Shima, Science 2016, 354, 114. We found very long electron wires made of iron-sulfur clusters, which connect the four tungsten-containing active sites. 5“Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction”: T. Wagner, J. Koch, U. Ermler, S. Shima, Science 2017, 357, 699. We found a new type of iron-sulfur cluster. Volume58, Issue24June 11, 2019Pages 7910-7910 ReferencesRelatedInformation