Abstract

Background Cardiac MR (CMR) has emerged as the gold standard in assessing biventricular size and systolic function with segmented balanced steady-state free-precession (bSSFP) cine acquisitions. The application of a novel prototype iterative reconstruction technique to sparsely undersampled segmented bSSFP cine acquisitions may enable higher acceleration factors while shortening image acquisitions, thus maintaining adequate image quality for quantitative analysis. The purpose of this study is to evaluate the clinical utility of a segmented sparsely sampled 2D CINE imaging technique, with a prototype iterative SENSE reconstruction using L1-regularization, in the quantitative assessment of right ventricular (RV) systolic function.

Highlights

  • Cardiac MR (CMR) has emerged as the gold standard in assessing biventricular size and systolic function with segmented balanced steady-state free-precession cine acquisitions

  • The purpose of this study is to evaluate the clinical utility of a segmented sparsely sampled 2D CINE imaging technique, with a prototype iterative SENSE reconstruction using L1-regularization, in the quantitative assessment of right ventricular (RV) systolic function

  • 9 healthy volunteers (44.3 ± 13.5 yrs) and 29 patients (54.3 ± 13.8 yrs) with suspected cardiac pathology were scanned on a 1.5T scanner (MAGNETOM Aera, Siemens AG, Healthcare Sector, Erlangen, Germany)

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Summary

Introduction

Cardiac MR (CMR) has emerged as the gold standard in assessing biventricular size and systolic function with segmented balanced steady-state free-precession (bSSFP) cine acquisitions. The application of a novel prototype iterative reconstruction technique to sparsely undersampled segmented bSSFP cine acquisitions may enable higher acceleration factors while shortening image acquisitions, maintaining adequate image quality for quantitative analysis. The purpose of this study is to evaluate the clinical utility of a segmented sparsely sampled 2D CINE imaging technique, with a prototype iterative SENSE reconstruction using L1-regularization, in the quantitative assessment of right ventricular (RV) systolic function

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