Abstract

Accurate lung segmentation in chest radiographs is a challenging problem due to the presence of strong edges at the rib cage and clavicle, the varying appearance in the upper clavicle bone region, too small costophrenic angle and the lack of a consistent anatomical shape among different individuals. In this paper, we propose a hybrid semi-automatic method called Hull-Closed Polygonal Line Method (Hull-CPLM) to detect the boundaries of the lung Region of Interest (ROI). To the best of our knowledge, this is the first attempt at lung segmentation using the Hull-CPLM in chest radiographs. The proposed method has two main steps: 1) an image preprocessing method is constructed to implement the coarse segmentation by using as low as 15% of the manually delineated points as the initial points, 2) a refinement step is used to fine-tune the segmentation results based on the improved principal curve model and the machine learning model at the refinement step. To prove the performance of the proposed method, both the private and public databases were used. The private database is used to select the optimal parameters for the proposed method, where the result showed a good performance with the Dice Similarity Coefficient (DSC) as high as 97.08%. While on the public databases, our proposed algorithm not only surpassed the performance of different hybrid algorithms but also reached superior segmentation results by comparing with state-of-the-art methods.

Highlights

  • Pulmonary cancer is one of the leading causes of death and hospitalization worldwide [1]

  • EXPERIMENTAL RESULTS In order to prove the universality of the proposed model, the private hospital database and the four public databases are used as the research object to evaluate the performance of the proposed algorithm

  • The private hospital database is used to select the optimal performance of the proposed method in detail (Section III-C)

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Summary

Introduction

Pulmonary cancer is one of the leading causes of death and hospitalization worldwide [1]. The lung images are always used for monitoring and analyzing the organ, which is an important strategy for the early diagnosis of pulmonary cancer [2], [3]. In the early stage of lung cancer, the radiologists can be assisted with the Computer Aided Diagnosis system (CAD) to detect abnormal tissue areas of the lungs, so as to improve diagnostic accuracy. Accurate lung segmentation is often performed as a necessary stage on quantitative and qualitative lung image analysis because it is important for identifying lung cancer in clinical evaluation. Research on lung segmentation has always received much attention. Researches have proposed several algorithms for lung segmentation in recent years [4]–[6], while accurate lung segmentation continues to require more attention because of the heterogeneity of the organ

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