Abstract
SummaryIn an open controlled trial of ibuprofen in the long-term treatment of osteoarthrosis of the hip, 35 patients received 1200 mg. ibuprofen daily over a period of 6 months. Seven patients discontinued treatment after 2 months because of remission of all symptoms and 7 others were withdrawn (2 due to side-effects, 5 for non-medical reasons). Subjective and objective assessments were carried out at monthly intervals. The results showed that pain was significantly reduced, particularly during the first 2 months, and there was a marked reduction in the need for additional analgesics. There was also a significant improvement in joint mobility within the first few months of treatment. Ibuprofen was well tolerated and side-effects were minimal.
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