Abstract
Chronic experiments were staged on 9 dogs with multipolar electrodes implanted into the hypothalamus. The amount of saliva secreted and the rate of its secretion in hypothalamic stimulation depends on the frequency and the stimulating current. The maximum amount of saliva secretion is observed at 40 pulses per sec (pulse duratio— 0.2 millisec, 0.7–0.8 and the sinusoid current of 0.5–0.6 mA (frequency 40–50 cycles per sec). Prolonged stimulation of hypothalamus by rectangular current pulses provokes saliva secretion during the whole course of stimulation. Prolonged stimulation by a sinusoidal current causes the greatest secretory effect only during the first minute, after which in decreases considerably and is completely arrested in the 10th minute of stimulation. Salivary secretion also depends on the portion of hypothalamus stimulated.
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