Abstract
Peptides have been used as pharmaceuticals ever since 1922, when a diabetic patient at Toronto General Hospital was injected with an extract of canine pancreas. The area of peptide drug therapy is in a state of change. It is expanding from its ‘traditional’ niche of treating hormonal disturbances into the areas of cancer therapy or the treatment of physiological disorders. At the same time, new production processes are providing greater amounts of peptide so that a larger proportion of patients in the traditional areas receive the proper treatment. This review briefly describes the kinds of peptide drugs now or soon to be available and shows one way in which biotechnology is contributing to the development of peptide drug therapy.
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