Secondary organizing pneumonia following viral pneumonia caused by severe influenza B: a case report and literature reviews

Nobuhiro Asai,Yuka Yamagishi,Naoya Nishiyama,Daisuke Sakanashi,Yusuke Koizumi,Hideo Kato,Mao Hagihara,Hiroshige Mikamo,Toyoharu Yokoi,Hiroyuki Suematsu

doi:10.1186/s12879-017-2677-1

Nobuhiro Asai, Yuka Yamagishi + Show 8 more

Open Access

https://doi.org/10.1186/s12879-017-2677-1

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Abstract

BackgroundSome reported that organizing pneumonia (OP) may occur after influenza A infections including swine-origin influenza A (H1N1). However, OP associated with influenza B infection has never been reported. We report the first case of secondary OP associated with viral pneumonia caused by influenza B.Case presentationA 23-year old woman was diagnosed as viral pneumonia caused by type B influenza. Despite of antiviral therapy, abnormal chest shadows were not improved. Bronchoscopy and transbronchial lung biopsy showed organizing pneumonia due to viral pneumonia caused by influenza B. Corticosteroid therapy was started at 30 mg daily (0.5 mg/kg), and the dose was reduced to 25, 20, 15 or 10 mg per day every month with symptomatic and radiological resolution. Even after corticosteroid therapy was discontinued, we did not confirm disease recurrence.ConclusionsPhysicians should be aware of the possibility for SOP and severe viral pneumonia even in case of type B as well as type A influenza infections.

Highlights

BackgroundOrganizing pneumonia (OP) is a pulmonary inflammatory condition that occurs in certain clinical settings [1, 2]
Some reported that organizing pneumonia (OP) may occur after influenza A infections including swine-origin influenza A (H1N1)
Physicians should be aware of the possibility for SOP and severe viral pneumonia even in case of type B as well as type A influenza infections

Summary

Background

Organizing pneumonia (OP) is a pulmonary inflammatory condition that occurs in certain clinical settings [1, 2]. Some reported that OP may occur after influenza A infections including swine-origin influenza A (H1N1) [3,4,5]. OP associated with influenza B infection has never been reported. We report the first case of secondary OP associated with viral pneumonia caused by influenza B. Case presentation A 23-year old woman without relevant medical history visited our outpatient clinic complaining fever, sorethorat and cough lasting for 3 days. She was diagnosed as influenza B infection by nasophayngeal antigen test

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