Secondary metabolites with chemotaxonomic value from Paecilomyces marquandii

Abstract

A systematic investigation on the secondary metabolites of Delphinium-associated fungus Paecilomyces marquandii afforded eight compounds, including six sorbicillinoid polyketides (1–6) and two ergosterol sterols (7–8). Among them, six compounds (1–5, 8) were identified for the first time from the genus Paecilomyces, and seven compounds (1–5, 7–8) have not previously been found in the fungus P. marquandii. The chemotaxonomic significance of these compounds was discussed. Some of the isolates (2, 5, and 6) showed limited distribution and could serve as chemotaxonomic markers to facilitate strain identification of P. marquandii.