Abstract
Abstract The marine fungus Paradendryphiella arenariae BCC 17999, isolated from Thailand, was investigated for bioactive secondary metabolite production. Large-scale fermentation in liquid medium yielded several known compounds, including tricycloalternarenes 2b (also known as ACTG-toxin D), 3a, 3b, A, H, and 11a, as well as infectopyrone. Tricycloalternarenes 2b and 3b displayed weak cytotoxic activity against the human small-cell lung cancer cell line NCI-H187.
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