Abstract
Paecilomyces, a common saprobic filamentous fungus, not only plays an important role in biological control, but also has applications in medicine, food, and environmental protection. In this paper, 223 secondary metabolites and their bioactivities from 13 known species and various unidentified strains of Paecilomyces are reviewed. Their structures can be described as polyketide, terpenoid, peptide, alkaloid, quinone, pyrone, sterol, and fatty acid. They have been demonstrated varying biological activities, including antimicrobial, antitumor, insecticidal, antiplasmodial, antimalarial, nematicidal, herbicidal, and enzyme-inhibiting. This review provides a comprehensive overview of secondary metabolites and their biological activities from strains of Paecilomyces.
Highlights
Paecilomyces is a common saprobic filamentous fungus
This review presents 223 secondary metabolites and their biological activities isolated from the 13 known species and various unidentified
As a result of the hardiness, wide adaptability, and ease of culture of most species of Paecilomyces, they play an important role in pest control, medicine, functional foods, environmental pollution control, and genetic engineering
Summary
Paecilomyces is a common saprobic filamentous fungus. It is found in a wide range of habitats, including soils, forests, grassland, deserts, sediments, and even sewage sludge [1]. Many species of Paecilomyces are important entomopathogenic fungi, which refer to a class that can infect or parasitize living host organisms and are an ecologically highly specialized group of micro-organisms. The entomopathogenic fungi belonging to the genus Paecilomyces have been extensively studied as potential biological control agents against insects. Paecilomyces is closely related to all aspects of human life and it plays an irreplaceable role in biological control, and has an important role in medicine and health. This review presents 223 secondary metabolites and their biological activities isolated from the 13 known species and various unidentified.
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