Abstract

Purpose Elevated serum parathyroid hormone (PTH) was previously reported in 8 African Americans (AAs) consecutively hospitalized in February 2005 with congestive heart failure (CHF) (Am J Med Sci 2006;331:30). The contribution of hypovitaminosis D to the appearance of secondary hyperparathyroidism (SHPT) was not addressed. Melanin is a natural sunscreen. Methods and Results Herein we report on SHPT (PTH > 65 pg/mL) and hypovitaminosis D (25(OH)D 30 ng/mL). We found (mean ± SEM): Conclusions Hypovitaminosis D is prevalent among AAs, with or without heart failure, whereas SHPT was confined to those with CHF where [Ca2+]o and [Mg2+]o balance can be compromised by chronic aldosteronism and loop diuretic. The potential for macro- and micronutrient supplements in the overall management of AA with heart failure is called into question.

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