Secondary glaucoma and visual outcome after paediatric cataract surgery with primary bag-in-the-lens intraocular lens.

Abstract

To determine predictors of secondary glaucoma and poor visual outcome in children undergoing cataract surgery with bag-in-the-lens (BIL)-IOL implantation. Medical records were retrospectively analysed for children with primary implantation with BIL-IOL during 2009-2013. The study included 109 eyes. Median age at surgery was 2.5years (range 2weeks-14.1years), 26.6% being ≤12weeks of age (=early group). Median follow-up time was 2.8years (7months-5.8years). 15 eyes (13.8%) developed glaucoma, 14 (48.3%) in the early group and 1 (1.3%) in the late group (p<0.001). Within the early group, mean time for surgery differed significantly. Patients developing glaucoma had cataract surgery at 3.5±1.1weeks (mean±SD) and the non-glaucoma patients at 5.7±3.3weeks (p=0.024). In the entire cohort, 21 eyes (19.3%) had conditions associated with glaucoma; 57.1% of these developed glaucoma compared to 3.4% without these conditions (p<0.001). Corrected distance visual acuity (CDVA) (decimal) of ≥0.5 was seen in 50 eyes (48.5%), median 0.63 in the late group and 0.15 in the early group. Glaucoma eyes in the early group (surgery at 3.5weeks) achieved 0.56 median (range, 0.4-1.0) logMAR, (0.28 decimal) CDVA, whereas non-glaucoma eyes (surgery at 5.7weeks) achieved 0.89 median (range 0.7-1.6) logMAR (0.13 decimal) CDVA; p=0.016. Glaucoma development in infants between 5weeks and 2years of age was 6.7% (n=2/30). Comorbidity strongly increases the risk of secondary glaucoma. Surgery during the first month is correlated with better CDVA outcome and glaucoma. After 5weeks of age, glaucoma rate is low with the BIL-IOL.