Secondary gastric cancer malignancies following a breast cancer diagnosis: A population-based analysis

Abstract

ObjectiveTo quantify the population-risk of developing gastric cancer (GC) following breast cancer (BC). MethodsGC incidence following a ductal or lobular BC were separately compared to incidence in the general United States population using SEER data. ResultsGC rates were similar to the general population for ductal BC. Women aged 35–75 with lobular BC had a significantly higher incidence of GC; women aged 40–44 had the highest risk. ConclusionThe risk of secondary GC is high among young women diagnosed with lobular BC. More studies investigating the etiology and prevalence of familial GC syndromes at the population-level are needed.