Abstract
Secondary central nervous system lymphoma (SCNSL) is known as a rare disease. The risk factor of developing SCNSL is primary lymphoma type and site of involvement. We present a patient with an altered mental status known case of breast diffused large B-cell lymphoma (DLBCL) who underwent stereotactic biopsy because of a left periventricular mass lesion, which diagnosed as secondary brain lymphoma after pathologic typing. Because of limited data about the secondary central nervous system, lymphoma and it is a risk factor, we reported an aggressive breast DLBCL with brain involvement.
Highlights
Secondary central nervous system lymphoma (SCNSL) is a lymphoma not derived from central nervous system (CNS) and can be a recurrence in the CNS or a part of a progressive disease.[1]
The patient had muscle weakness, right side paresis and was ill but not toxic. She had a medical history of breast lymphoma type diffused large B-cell lymphoma (DLBCL) 18 months ago, which treated with chemotherapy and radiotherapy
The incidence of SCNSL depends on the type of primary lymphoma, the involvement of more than one site, stage of the primary disease and grade of the International Prognostic Index.[1,2] patient with involvement of the breast, testis, and bone marrow as the primary disease is at a higher risk of developing SCNSL.[4]
Summary
Secondary central nervous system lymphoma (SCNSL) is a lymphoma not derived from central nervous system (CNS) and can be a recurrence in the CNS or a part of a progressive disease.[1]. Introduction Secondary central nervous system lymphoma (SCNSL) is a lymphoma not derived from central nervous system (CNS) and can be a recurrence in the CNS or a part of a progressive disease.[1] It is typically a non-Hodgkin lymphoma. SCNSL divided into subtype, leptomeningeal and parenchymal, or as a combination of this two type.
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