Abstract
COVID-19 disease is a global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) that mainly presents with pneumonia, but has variable multi-systemic manifestations. Concomitant bacterial infections associated with the acute stage of COVID-19 disease have been rarely reported in the literature. However, to our knowledge, post viral organizing pneumonia (OP) secondary to bacterial infection after recovery from SARS-CoV2 infection has not been noted before. We report a 27-year-old male patient with Type 1 Diabetes Mellitus who presented with fever post recovery from COVID-19 disease for seven weeks and was found to have OP secondary to Klebsiella pneumoniae. Furthermore, the bronchoalveolar lavage was positive for SARS-CoV2 by RT-PCR despite multiple negative nasopharyngeal RT-PCR. The patient was successfully treated with antibiotics only. Therefore, we conclude that early recognition of OP secondary to bacterial infection in patients with COVID-19 disease and prompt antibiotic treatment could avoid the use of a prolonged course of steroids.
Highlights
COVID-19 disease was announced as a pandemic by the World Health Organization (WHO) on March 11th, 2020
COVID-19 disease is a global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) that mainly presents with pneumonia, but has variable multi-systemic manifestations
We report a 27-year-old male patient with Type 1 Diabetes Mellitus who presented with fever post recovery from COVID-19 disease for seven weeks and was found to have organizing pneumonia (OP) secondary to Klebsiella pneumoniae
Summary
COVID-19 disease was announced as a pandemic by the World Health Organization (WHO) on March 11th, 2020. It is caused by a novel virus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) [1]. The most common post viral bacterial infections are caused by Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae [2]. This is true for SARS-CoV2 infection with 0% - 15% of patients found to have concomitant bacterial infection [3]. OP tends to respond to corticosteroids as first line treatment for this condition [6]
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