Abstract
Sebaceous carcinoma (SC) is an aggressive, malignant tumor derived from the adnexal epithelium of sebaceous glands that can occur in ocular/periocular (75 % of all SC) and extraocular variants. Its incidence varies according to the ethnicity. In Caucasians, SC accounts for 1.5–5 % of eyelid malignancies, while in Asiatic people, it is the second most common eyelid malignancy after basal cell carcinoma with an incidence of 38 %. Ocular SC occurs more frequently in women (3:1), while the extraocular form has a predilection for men (2:1). The age of presentation varies from 60 to 80 years. SC may occur in the setting of Muir–Torre syndrome, after radiotherapy or in immunocompromised patients such as HIV-infected patients.
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