Abstract

1. 1. The concentration of IgG2 in serum of non-hibernating hedgehogs was fairly constant, 16 mg/ml. During hibernation the concentration fell steadily to reach the lowest value in March–April and then rose again after termination of hibernation. 2. 2. The mean decrease in serum concentration of IgG2 in two hibernating animals studied more closely was 0·05 mg/ml per day. 3. 3. The half-life of IgG2 in non-hibernating hedgehogs was 2·2 days. The half-life was prolonged to as much as 40 days in hibernating animals.

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